Attempted To Read Or Write Protected Memory. This Is Often An Indication That Other Memory?

I am maintaining C# .NET code written by somebody else, I get following exception few times,Attempted to read or write protected memory. This is often an indication that other memory is corruptThe code structure where I get the above exception is somethign like this,- it is using ref variables in following sequence,Variable-1 and variable-2 are local variables in App1, - App1: func1() which passes these variables reference to func2(), - App1: func2() passes same variables reference via .net remoting to another application (App2).-App2: does the same passes same received reference to another call 2 times.- The execption is occured while returning from App2.

(App1:func1(ref Var1, ref Var2) --> App1:func2(ref Var1, ref Var2) <---App1 .net remoting to App2--> App2:func3(ref Var1, ref Var2)--> App2:func4(ref Var1, ref Var2)-->variables getting updated and function returned to original caller)

My doubts are ,1. Is passing reference variables in such chain is correct? will it cause such exeption? Does .net support ref variable call directly?